BIP Specialities Fine Chemical Manufacturing

BIP Specialities has delivered sustainable chemical processing by recovering and recycling for over 25 years. Our speciality resides in research and development of fine chemicals particularly from lab research, lab trials to full plant scale-up for bespoke molecules and ester synthesis.

We use our flexible resources and substantial experience to deliver valuable materials back to our customers. Where possible we return viable product recovery from waste streams, which we feel is more innovative and environmentally friendly.

Our expertise allows us to form strong relationships with our customers, enabling them to focus on core activities by assisting them with subsidiary problems – process development / optimisation, new product development, waste minimisation, or improving raw material and energy utilisation.

We offer full toll and custom manufacturing services.

Some methodologies we have put into manufacturing include Friedel-Crafts, Mitsunobu, SNAr, Esterifi ation, Amidation, Lactam cyclisation, and catalytic variants of the Ullmann and Goldberg reactions. Initial evaluation of your project is available free of charge, and we can develop and optimise a process for you from as little as a basic reaction scheme.

Since inception in 1991, we have worked with many satisfied customers from small one off jobs to many years of exclusive manufacture on large scale for multinational partners.

BIP Specialities Facilities

BIP Specialitis have full in-house engineering capabilities, plant and laboratory facilities. This agility and flexibility gives niche competitive advantage.

Some of our facilities are listed below.

Over 320,000 L of total processing capacity
Mix of glass-lined and stainless steel vessels, 100 L to 30,000 L
Services include vacuum to 1 mbar, hot oil to 250°C, Steam to 100 psi, Cryogenic capability
Pressure reactions to 100 Bar
Large scale vacuum fractionation (8, 11, 22 and 32 plate columns) and single plate distillation
Wide choice of filtration equipment
Up to 48 inch centrifuges, Funda filter, pan filters, agitated filter/drier
700 L, 2000 L, and 2 x 6000 L vacuum powder driers
Over 1,500,000 L of bulk storage including
Bunded drum storage area
Two tanker weighbridges
Modern Process Research Laboratory.
Radleys parallel experimentation equipment
Lab scale jacketed vessels to mimic plant equipment (1 L – 20 L), data logging
Literature searching via Reaxys to apply innovative methodology where appropriate
On-site HPLC, GC, XRF, UV/vis and FTIR analysis
Next day NMR and LC-MS contract service
Full In-house engineering design and fabrication capability
Pipefitting, machining, plasma arc cutting, coded welding.
Extensive spare plant inventory

BIP Specialities Services

Custom Research, Development and Manufacturing

We utilise our extensive experience to develop and optimise a process which can be scaled on-site from small quantities to full scale manufacture as your requirements evolve.

- Successful Fine Chemicals Division
- Decades of experience in Process Development and New Product Introduction
- Fully equipped modern Process Research laboratory
- Comprehensive selection of commercial scale equipment
- Breadth of experience executing following methodologies into production – Mitsunobu, Friedel Crafts, [Cu] catalysed Ullmann and Goldberg reactions, formation of hindered amides or highly labile esters, SNAr, Etherification, Epoxidation, and Lactam cyclisation.
- Examples of main product classes produced (but not limited to):
  - Alkoxy substituted benzoic acids (with possible further ring halogenation)
  - Alkoxy substituted phenols (with possible further ring halogenation)
  - Alkoxy substituted anilines (with possible further ring halogenation)
  - Substituted diaryl esters
  - Metal 2-ethylhexanoates (octoates)
  - Iron 2-ethylhexanoate
  - Solutions of Sodium 2-ethylhexanoate and Chromium 2-ethylhexanoate
  - Zinc and Bismuth Octoate products
  - Potassium 2-ethylhexanoate
  - Cobalt 2-ethylhexanoate
  - Tin 2-ethylhexanoate (Such products can be supplied in a variety of solvents at the user’s choice. For example, we have supplied Iron EHA as a 50% solution in white (mineral) spirit, gas oil, or toluene)
  - We have manufactured a range of Coumarins, leading examples are the laser dye Coumarin 152 (7-Dimethylamino-4-trifluoromethylcoumarin) and Coumarin 311 (7-Dimethylamino-4-methylcoumarin)
  - 1,3,5-Triaryl Benzenes
  - We currently produce the parent 1,3,5-Triphenylbenzene (high purity)
  - 1,3,5 Tri-(4-bromophenyl)benzene and 1,3,5 Tri-(4-methoxyphenyl)benzene
  - Squaraine Dyes, Dihydroperimidine squaraine dye
  - Legacy terms for this product are WDR3 and PSA1345
  - Speciality Benzophenones -We have experience in producing a range of benzophenones, and are most interested in value added or rare structures
  - Ether ditosylates, such as Ethylene glycol ditosylate, Diethylene glycol ditosylate
  - 1,3 Diones such as Benzoyl acetone, 1,3-Di(4-methoxyphenyl)propan-1,3-dione
  - 4-OH TEMPO (high purity) and derivatives such as 4-Benzyloxy TEMPO